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COVID Vaccine May Increase the Risk of Prion Disease


By:  David Deschesne

Fort Fairfield Journal, March 24, 2021


   Dr. J. Bart Classen, MD recently published a research article in the journal Microbiology & Infectious Diseases that discussed the risk of prion disease associated with the current experimental mRNA COVID-19 vaccines.1

   Prions are protein particles that caused “mad cow” disease in cattle over a decade ago and create Alzheimer’s - like symptoms in humans.

   Dr. Classen looked at Pfizer’s RNA-based COVID-19 vaccine, which was approved by the U.S. FDA under an emergency use authorization without any long term safety data.   The Emergency Use classification means the vaccine is for experimental use and it has not yet received any FDA confirmation of safety or efficacy and is technically not yet “approved” by the FDA.  He found the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations.

   “Analysis of the Pfizer vaccine against COVID-19 identified two potential risk factors for inducing prion disease [in] humans.  The RNA sequence in the vaccine contains sequences believed to induce TDP-43 and FUS to aggregate in their prion based conformation leading to the development of common neurodegenerative disease,” wrote Dr. Classen.  “...the concern is raised that the RNA based COVID vaccines have the potential to cause more disease than the epidemic of COVID-19.”

   Dr. Classen notes how over the past two decades there has been a concern among certain scientists  that prions could be used as bioweapons.  “More recently there has been a concern that ubiquitous intracellular molecules could be activated to cause prion disease including Alzheimer’s disease, ALS and other neurodegenerative diseases.”

    Because the diseases the vaccines can potentially cause are already pre-existing and take years to express themselves, the vaccine manufacturers will successfully be able to defend themselves against adverse public opinion because it will be so difficult to connect the manifestation of those diseases in vaccine recipients years or decades after they received the vaccine.

   Dr. Classen says the “viral spike protein, coded by the vaccine RNA sequence, binds ACE2 an enzyme containing zinc molecules.  This interaction has the potential to increase intracellular zinc levels leading to prion disease.”

   There are other potential adverse effects of the COVID-19 vaccines.  “The vaccine places a novel molecule, spike protein, in/on the surface of the host cells,” explains Dr. Classen.  “This spike protein is a potential receptor for another possibly novel infectious agent.  If those who argue COVID-19 is actually a bioweapon are correct, then a second potentially more dangerous virus may be released that binds spike protein found on the host cells of vaccine recipients.” 

   He also points out that “Data is not publicly available to provide information on how long the vaccine RNA is translated in the vaccine recipient and how long after translation the spike protein will be present in the recipient’s cells.”

   He also explains how genetic diversity protects species from mass casualties caused by infectious agents.  “One individual may be killed by a virus while another may have no ill effects from the same virus.”

   But, he points out that “by placing the identical receptor, the spike protein, on cells of everyone in a population, the genetic diversity for at least one potential receptor disappears.  Everyone in the population now becomes potentially susceptible  to binding with the same infectious agent.”

   He concludes that “approving a vaccine, utilizing novel RNA technology without extensive testing is extremely dangerous.  The vaccine could be a bioweapon and even more dangerous than the original infection.”